Monday to Sunday, including holidays: 8h - 20h
Phone number: 282 420 020
Av. S. João de Deus - Parque de Saúde da Misericordia de Portimão,
8500-508 Portimão
Opening Hours
Monday to Friday: 7am - 10pm
Saturdays, Sundays and Bank Holidays: 8 am - 10 pm
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Daily: 8am - 9pm
Clinical Analysis
Monday to Friday: 7am - 8pm
SaturdaySunday and Bank Holidays: 8am - 8pm
Av. General Humberto Delgado, Lote 7 7520-103 Sines
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Hospital Particular Alvor
00h00mUrgent Care
Hospital Particular Gambelas
00h00mUrgent Care
00h00mPaediatrics
Hospital Particular da Madeira
00h00mUrgent Care
00h00mPaediatrics
Madeira Medical Center
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HPA Magazine 14
The research is entitled “Obstructive Sleep Apnoea: The Effects of Apnoea-Hypopnea Index, Oxygen Desaturation and Daytime Sleepiness on Cognitive Function” and aims to understand the causes of neuro-cognitive decline in patients with Obstructive Sleep Apnoea (OSA), namely those associated with apnoea-hypopnea, oxygen desaturation and daytime sleepiness.
The results revealed impairment in the general cognitive performance of severely affected patients, but no deficit was observed in patients with mild and moderate OSA. Although no other evidence of cognitive impairment was found in patients when analysed according to the severity of the disease, an analysis that included all apnoea patients revealed an increase in deficit of attention, memory and cognitive flexibility. The severity of the disease, desaturation and excessive daytime sleepiness, did not contribute significantly to the development of most of these deficits, suggesting that other mechanisms not explored in this study may be involved.
The results revealed, however, that excessive daytime sleepiness has a negative influence in the capacity for inhibitory control in patients with OSA, confirming the harmful effects in the prefrontal cortex circuit of sleep interruption and poor sleep quality. Overall, this study emphasizes the impact of OSA on cognition, regardless of the severity of the disease, as well as the importance of psychological aspects of this disorder.
The research resulted from a partnership between the Algarve University (UALg) and the HPA, and was part of the Master's Degree in Cognitive Neurosciences and Neuropsychology. Miguel Coutinho (Neuropsychologist of the HPA Group), Laura Nedel Duarte (Neuropsychology Intern at UALg), Vinícius Duarte (Neurophysiology Technician at the HPA Group) and Dina Silva (Researcher and Professor at UAlg) were part of the group of researchers.